【陈巍学基因】视频119: twinPE 大片段基因编辑
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twinPE 是 prime editing 技术的拓展。twinPE 可以对活细胞中的大片段基因做编辑，包括：修改、插入、删除、和颠倒。本视频介绍了这项技术的工作原理，和做基因大片段的修改、插入、删除、和颠倒的实例。
参考文献：Andrew V. Anzalone, Xin D. Gao, et al. Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing [J] nature biotechnology, 09 December 2021, doi.org/10.1038/ s41587-021-01133-w
参考文献：Andrew V. Anzalone, Xin D. Gao, et al. Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing [J] nature biotechnology, 09 December 2021, doi.org/10.1038/ s41587-021-01133-w
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